Why Don’t My Anti-Wrinkle Injections Last Like They Used To
- IOANA MARCU

- Oct 25
- 3 min read

You used to love the results.They kicked in fast.
They smoothed everything. You felt fresh.
But lately…😩 The effect wears off too soon😶 It feels heavy or “off”🤷♀️ And your face doesn’t bounce back like it used to
You’re not imagining it — and you're not alone.
At Pure Aesthetics Clinic, we recently saw a new client in her 40s who said:
“It’s not lasting 3 months anymore… and it just feels heavier. I don’t recognise myself like I used to.”
Here’s what might be happening 👇
📍 1. Repeated Use Without Assessment
If you’ve had anti-wrinkle injections repeatedly without proper review or adjustment, your treatment might be:
Overdosed → too much product causing heaviness or flatness
Underdosed → not enough to fully relax the muscle
Misdosed → injected in areas that aren’t actually the problem anymore
🧠 Your face changes over time. So should your treatment plan.
⚔️ 2. Muscle Compensation or Resistance?
In rare cases, your muscles may compensate — meaning when one muscle is relaxed repeatedly, others work harder. This can cause:
New lines appearing in unusual places
A feeling of weight or imbalance
Faster movement return in the usual areas
True resistance (when your body makes neutralising antibodies) is extremely rare — but can happen in long-term users, especially if they've received very high doses or been treated too frequently.
👉 According to a study in the Journal of Neurology (2018), resistance is mostly seen in therapeutic patients receiving repeated high-dose toxin treatments (e.g., for dystonia or spasticity), not standard aesthetic doses.
So what you're experiencing is more likely dose fatigue, not full immunity.
🧬 3. Your Body Changes — So Must the Plan
Factors like:
Stress
Hormonal shifts (perimenopause, HRT, etc.)
Metabolism
Illness
Medications (like antibiotics, steroids)
… can all affect how your body responds to anti-wrinkle treatment.
👩⚕️ If your practitioner isn’t regularly reassessing dosage, product, or placement, your results may not feel “right” anymore — because your body isn’t the same as it was 5 years ago.
💡 What We Do Differently at Pure Aesthetics Clinic
Every anti-wrinkle consultation at our clinic is:
Personalised – your face, your lifestyle, your goals
Safe – using UK-approved medical-grade products
Evaluated over time – we don’t just inject; we review
We also educate clients when it’s time to:
Take a break
Try a different treatment area
Combine with skin health treatments (like microneedling or mesotherapy)
Consider switching products (if medically indicated)
🗓️ And yes — sometimes, it’s time to press pause.
✨ Case Study: “Not Lasting Anymore, and Felt Heavy”
💬 A woman in her 40s came to us after years of regular anti-wrinkle treatments elsewhere.
She felt:
“I don’t feel like myself anymore. The results are less and less.”
On examination, we found:
Repetitive injection in the same zones
Little to no facial balance
Weak upper forehead muscle + overactive compensatory muscles
We adjusted her dose and spread her follow-ups to every 5–6 months instead of 3.
After two sessions:
“I feel like me again — just fresher.”
📌 Final Thoughts
If your anti-wrinkle results aren’t lasting — or feel “off” — don’t ignore it. It could be a sign your treatment plan needs updating… or your face needs a little reset.
You deserve personalised care, not copy-paste injections.
We offer free consultations at Pure Aesthetics Clinic — whether you're a first-timer or someone who’s fallen out of love with your previous results.
Book now or learn more →https://www.pure-aesthetics-clinic.co.uk/
🧠 Next Blog Tease:
✨ “Do I Need a Break from Anti-Wrinkle Injections?”
We’ll explore the signs, benefits, and whether pausing your treatment could actually help you look better long term.






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